brandon1977 wrote:It's not just anger. I have extremely bad anxiety. It's been that way my whole life. It's held me back from almost everything. I have an appointment with a doc for some meds to try and sort that out. I don't think I've really ever felt happy inside maybe. I feel like the anger is a byproduct of my stress that's just never under control.
I'm tired of worrying constantly. I'm tired of being stressed. It's ruining everything.
Hi Brandon. NO! Do not let them put you on any of the Serotonin Reuptake Inhibitor drugs (and that is what everything is nowadays... the same drug, modified to get around patent protections (which means that we've lost track of the good most effective drug while everybody is churning out Second Bests to get in on the action).
Just do some on line searches. Start with
https://en.wikipedia.org/wiki/Selective ... t_of_SSRIsHere is a short List of the things: Marketed
Neurotransmitter transporters inhibitors
Serotonin transporter inhibitors
Antidepressants
Citalopram (Celexa)
Escitalopram (Lexapro)
Fluoxetine (Prozac)
Fluvoxamine (Luvox)
Paroxetine (Paxil)
Sertraline (Zoloft)
Structures
Others
Dapoxetine (Priligy)
Structures
Discontinued
Antidepressants
Indalpine (Upstène)
Zimelidine (Zelmid)
Structures
Never marketed
Antidepressants
Alaproclate (GEA-654)
Centpropazine
Cericlamine (JO-1017)
Femoxetine (Malexil; FG-4963)
Ifoxetine (CGP-15210)
Omiloxetine
Panuramine (WY-26002)
Pirandamine (AY-23713)
Seproxetine ((S)-norfluoxetine)
Structures
Related drugs
Although described as SNRIs, duloxetine (Cymbalta), venlafaxine (Effexor), and desvenlafaxine (Pristiq) are in fact relatively selective as serotonin reuptake inhibitors (SRIs).[150] They are about at least 10-fold selective for inhibition of serotonin reuptake over norepinephrine reuptake.[150] The selectivity ratios are approximately 1:30 for venlafaxine, 1:10 for duloxetine, and 1:14 for desvenlafaxine.[150][151] At low doses, these SNRIs act mostly as SSRIs; only at higher doses do they also prominently inhibit norepinephrine reuptake.[152][153] Milnacipran (Ixel, Savella) and its stereoisomer levomilnacipran (Fetzima) are the only widely marketed SNRIs that inhibit serotonin and norepinephrine to similar degrees, both with ratios close to 1:1.[150][154]
Vilazodone (Viibryd) and vortioxetine (Trintellix) are SRIs that also act as modulators of serotonin receptors and are described as serotonin modulators and stimulators (SMS).[155] Vilazodone is a 5-HT1A receptor partial agonist while vortioxetine is a 5-HT1A receptor agonist and 5-HT3 and 5-HT7 receptor antagonist.[155] Litoxetine (SL 81-0385) and lubazodone (YM-992, YM-35995) are similar drugs that were never marketed.[156][157][158][159] They are SRIs and litoxetine is also a 5-HT3 receptor antagonist[156][157] while lubazodone is also a 5-HT2A receptor antagonist.[158][159]
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My concern is that nearly all the effectiveness studies relate to patients INITIAL response to the drugs. But long term studies show that people's Body Chemistry tends to revert to NORMAL. Brandon, the drug effectively takes your body by surprise and things change for a while, but the body fights to get back to it's own normal. People need to up their dosages. Then there are the Side effects.
Then there is the Withdrawal Trap. It is harder to get off of these things then heroin. I was just on a low dosage for a a while some 20 years ago. The stuff never helped any in the first place. You see, Brandon, we live in a Puritanical World where the Food and Drug Administration refuses to allow any simple Euphoric Drug on the Market. Drugs have to cure or ameliorate pathological symptoms. Just making people feel BETTER is not enough. So the SSRI Drugs DON'T make you feel better, just different. Nothing changed for me and so i stopped but then WOW! it was terrible. Vertigo so bad you wouldn't know up from down. then there was YEARS of Brain Zaps. At first they were longish... a second or two. A Brain Zap is like an electric shock that seems to shut down your who nervous system, you actually begin to fall down. I think the heart must stop. All balance is lost. Damn! I used to ride a motorcycle. Imagine being in the middle of a turn and suddenly getting a Brain Zap that makes you DEAD for a second. And they go on for years, though milder.... still happens when I have been napping and first wake up and rise to my feet, there will be the SKITCH that happens in my brain where you still get the idea that for that fraction of a second everything just shuts down. Brandon, the Pharmaceutical Companies that turn out this POISON are making billions of dollars. The Politicians are being paid off. Everybody is afraid to quit these things because of the side effects. The dosage goes up over time. I've heard the DOCTORS are given REBATES to get new patients HOOKED. Brandon, stay away from that BUZZ-SAW. It would be just one more problem and don't you already have a full plate of crap that you have to choke down? And, remember, your Doctor is not your friend. Whatever you are paying him now is nothing compared to the amount he will get rebated every time your renew your prescription for the rest of your life.... I've heard some Doctors have been able to retire in their Forties on just the rebates coming in from people they hooked on these SSRIs.
So, yeah, I recently took Psych 101 for the second time in my life (to see if anything changed since the mid seventies). And, yeah, people each have their own baseline. My baseline is happy. Even when I'm miserable and depressed I'm still "cheerful". It makes it difficult to see what is going on. A few years back I was crippled with advanced degenerative osteoarthritis of the hip joints and the only way they could tell I was depressed was from a lot of the secondary marginal symptoms such as appetite and sleep pattern problems. But when I wasn't wincing in pain I was grinning. but with you, it is probably reversed. You are probably sort of glum even when you are "happy" or rather "content".
Brandon, be the person you are meant to be. Brandon, yeah, it's nice being "cheerful" but I also come across socially as shalllow... a light weight. Brandon, people would take you SERIOUS, right? There are worse things in the World.
Have you thought of writing Fiction. Anxiety would be a great back drop for Gothic, right?
Well, let me see what else you posted.....