Treatment Resistance

Anybody have any ideas on how I can break out of depression. It is a recurring problem for the last 14 years. I've tried therapy and medication and seem to always end up back to depression. At one point I had about 7-8 years symptom free but in the last three years I have been midly to moderately depressed. The doctors have tried almost every kind of medication and combinations thereof and nothing seems to pull me out. I hate to think this is what the rest of my life will be like...I've lost hope...suicide has never been an option but I need some relief. I see a new psychotherapist starting tomorrow.